And as the disease progresses, he becomes more and more detached from reality. RUFFALO: Thomas is a person living with schizophrenia in the show. GARCIA-NAVARRO: And how does Thomas view their relationship? But he's basically, in a big sense, given up his life because the amount of care that is needed is so great. But, you know, the way the immigrants survived was looking out for family in some regards. RUFFALO: You know, he comes from this Italian background that is so family-oriented - also full of family secrets. He has this push and pull between his wants and what he feels are his obligations, right? I want to start by talking about Dominick. And this dives straight into the heart of that by really looking at the relationship between these two brothers. Mental illness - right? - is such a complicated thing, especially in the way that it plays out in families - how they react, what effect it has. MARK RUFFALO: Thanks for having me, Lulu. The series finale is tonight, and Mark Ruffalo joins us now. Ruffalo also plays Thomas's twin, Dominick, whom he's both devoted to and resentful of. It's committed in a Connecticut library by Thomas, who has paranoid schizophrenia. It opens with an act of protest in the form of self-mutilation. "I Know This Much Is True" is a six-part series on HBO Max adapted from the best-seller of the same name.
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